# RV630 - Approach to Control HIV With Immune Enhancement and Vaccination (ACHIEV

> **NCT06484335** · PHASE1 · RECRUITING · sponsor: **Henry M. Jackson Foundation for the Advancement of Military Medicine** · enrollment: 48 (estimated)

## Conditions studied

- HIV Infections
- PLWH
- ART
- Acute HIV Infection

## Interventions

- **BIOLOGICAL:** VRC07-523LS
- **BIOLOGICAL:** PGDM1400LS
- **BIOLOGICAL:** ChAdOx1.tHIVconsv1
- **BIOLOGICAL:** ChAdOx1.HIVconsv62
- **BIOLOGICAL:** MVA.tHIVconsv4
- **BIOLOGICAL:** A244d11 gp120
- **BIOLOGICAL:** ALFQ
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT06484335
- **Lead sponsor:** Henry M. Jackson Foundation for the Advancement of Military Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-27
- **Primary completion:** 2027-08-01
- **Final completion:** 2027-08-01
- **Target enrollment:** 48 (ESTIMATED)
- **Last updated:** 2025-09-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06484335

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06484335, "RV630 - Approach to Control HIV With Immune Enhancement and Vaccination (ACHIEV". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT06484335. Licensed CC0.

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