# Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients

> **NCT06499389** · NA · RECRUITING · sponsor: **Hospices Civils de Lyon** · enrollment: 50 (estimated)

## Conditions studied

- Ventilator Weaning

## Interventions

- **PROCEDURE:** Systematic and early intensive instrumental respiratory physiotherapy for patients undergoing difficult ventilatory weaning
- **PROCEDURE:** Protocolized standard-of-care respiratory physiotherapy

## Key facts

- **NCT ID:** NCT06499389
- **Lead sponsor:** Hospices Civils de Lyon
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-18
- **Primary completion:** 2027-03-01
- **Final completion:** 2027-05-01
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2026-01-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06499389

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06499389, "Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients". Retrieved via AI Analytics 2026-07-25 from https://api.ai-analytics.org/clinical/NCT06499389. Licensed CC0.

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