# The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation

> **NCT06507449** · NA · ENROLLING_BY_INVITATION · sponsor: **Medical University of Silesia** · enrollment: 30 (estimated)

## Conditions studied

- Coronary Artery Calcification
- Ischemic Heart Disease
- Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
- Coronary Artery Disease
- Angina, Unstable
- Tomography, Optical Coherence

## Interventions

- **DEVICE:** Lithotripsy
- **DEVICE:** Orbital atherectomy
- **DEVICE:** High-pressure non-compliant balloon
- **DEVICE:** Optical coherence tomography
- **DEVICE:** Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire

## Key facts

- **NCT ID:** NCT06507449
- **Lead sponsor:** Medical University of Silesia
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2024-03-07
- **Primary completion:** 2026-06
- **Final completion:** 2026-12
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2025-11-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06507449

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06507449, "The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06507449. Licensed CC0.

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