Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

NCT06514898 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

12

Enrollment

OTHER

Sponsor class

Conditions

Recurrent Group 3 Medulloblastoma
Recurrent Group 4 (Non-SHH/Non-WNT) Medulloblastoma

Interventions

BIOLOGICAL: TTRNA-DC vaccines with GM-CSF
BIOLOGICAL: TTRNA-xALT
DRUG: Td vaccine
BIOLOGICAL: autologous HSCs
DRUG: Pembrolizumab

Sponsor

University of Florida

Collaborators

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