# A First-in-Human Safety Trial of MTX-474

> **NCT06535841** · PHASE1 · COMPLETED · sponsor: **Mediar Therapeutics** · enrollment: 78 (actual)

## Conditions studied

- Healthy

## Interventions

- **BIOLOGICAL:** MTX-474
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT06535841
- **Lead sponsor:** Mediar Therapeutics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-07-10
- **Primary completion:** 2025-04-24
- **Final completion:** 2025-04-24
- **Target enrollment:** 78 (ACTUAL)
- **Last updated:** 2025-05-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06535841

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06535841, "A First-in-Human Safety Trial of MTX-474". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT06535841. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
