# External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer

> **NCT06543576** · PHASE1,PHASE2 · RECRUITING · sponsor: **Jonsson Comprehensive Cancer Center** · enrollment: 35 (estimated)

## Conditions studied

- Cervical Adenocarcinoma
- Cervical Adenosquamous Carcinoma
- Cervical Squamous Cell Carcinoma
- Stage IVB Cervical Cancer American Joint Committee on Cancer (AJCC) v8

## Interventions

- **BIOLOGICAL:** Bevacizumab
- **PROCEDURE:** Biospecimen Collection
- **RADIATION:** Brachytherapy
- **DRUG:** Cisplatin
- **RADIATION:** External Beam Radiation Therapy
- **DRUG:** Paclitaxel
- **BIOLOGICAL:** Pembrolizumab
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT06543576
- **Lead sponsor:** Jonsson Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-29
- **Primary completion:** 2031-01-31
- **Final completion:** 2032-01-31
- **Target enrollment:** 35 (ESTIMATED)
- **Last updated:** 2025-08-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06543576

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06543576, "External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06543576. Licensed CC0.

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