# Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia

> **NCT06544798** · PHASE2 · ENROLLING_BY_INVITATION · sponsor: **MeiraGTx, LLC** · enrollment: 276 (estimated)

## Conditions studied

- Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

## Interventions

- **GENETIC:** AAV2-hAQP1

## Key facts

- **NCT ID:** NCT06544798
- **Lead sponsor:** MeiraGTx, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2024-08-02
- **Primary completion:** 2032-02
- **Final completion:** 2032-02
- **Target enrollment:** 276 (ESTIMATED)
- **Last updated:** 2025-10-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06544798

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06544798, "Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia". Retrieved via AI Analytics 2026-07-08 from https://api.ai-analytics.org/clinical/NCT06544798. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*