# Adaptive Hypofractionated Radiotherapy for Locally Advanced NSCLC Based on Dynamic Enhanced MRI

> **NCT06545747** · PHASE3 · RECRUITING · sponsor: **Sun Yat-sen University** · enrollment: 490 (estimated)

## Conditions studied

- Non-small Cell Lung Cancer

## Interventions

- **RADIATION:** DCE-MRI based split-course hypo-RT
- **RADIATION:** CT based split-course hypo-RT
- **DRUG:** Concurrent chemotherapy
- **DRUG:** Consolidative immunotherapy

## Key facts

- **NCT ID:** NCT06545747
- **Lead sponsor:** Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-08-01
- **Primary completion:** 2028-07-31
- **Final completion:** 2028-07-31
- **Target enrollment:** 490 (ESTIMATED)
- **Last updated:** 2026-04-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06545747

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06545747, "Adaptive Hypofractionated Radiotherapy for Locally Advanced NSCLC Based on Dynamic Enhanced MRI". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06545747. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*