# PROceeding With Advanced Techniques in Case of Distal Malignant Biliary Obstruction and Difficult Biliary Cannulation comparEd With Therapeutic-EUS: the PROMETHEUS Trial

> **NCT06550973** · NA · NOT_YET_RECRUITING · sponsor: **Istituto Clinico Humanitas** · enrollment: 220 (estimated)

## Conditions studied

- Malignant Biliary Obstruction

## Interventions

- **PROCEDURE:** pre-cut biliary sphincterotomy/fistulotomy, double guide wire (DGW) technique

## Key facts

- **NCT ID:** NCT06550973
- **Lead sponsor:** Istituto Clinico Humanitas
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2024-10-01
- **Primary completion:** 2026-09-30
- **Final completion:** 2026-09-30
- **Target enrollment:** 220 (ESTIMATED)
- **Last updated:** 2024-08-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06550973

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06550973, "PROceeding With Advanced Techniques in Case of Distal Malignant Biliary Obstruction and Difficult Biliary Cannulation comparEd With Therapeutic-EUS: the PROMETHEUS Trial". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT06550973. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*