# Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder

> **NCT06559995** · PHASE2,PHASE3 · RECRUITING · sponsor: **University of Pennsylvania** · enrollment: 30 (estimated)

## Conditions studied

- Alcohol Use Disorder
- Alcohol Withdrawal
- Ketosis

## Interventions

- **DIETARY_SUPPLEMENT:** ketone supplement "D-beta-hydroxybutryric acid and R-1,3 butanediol" 12g of ketones,
- **DIAGNOSTIC_TEST:** magnetic resonance imaging session
- **DIETARY_SUPPLEMENT:** Placebo beverage

## Key facts

- **NCT ID:** NCT06559995
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-08-01
- **Primary completion:** 2027-12
- **Final completion:** 2027-12
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2025-09-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06559995

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06559995, "Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT06559995. Licensed CC0.

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