# Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium

> **NCT06566469** · PHASE4 · COMPLETED · sponsor: **Peking University First Hospital** · enrollment: 340 (actual)

## Conditions studied

- Older Patients
- Nasal Administration
- Dexmedetomidine
- Esketamine
- General Anesthesia
- Emergence Delirium

## Interventions

- **DRUG:** Dexmedetomidine
- **DRUG:** Esketamine
- **DRUG:** Normal saline

## Key facts

- **NCT ID:** NCT06566469
- **Lead sponsor:** Peking University First Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-09-02
- **Primary completion:** 2025-03-28
- **Final completion:** 2025-05-01
- **Target enrollment:** 340 (ACTUAL)
- **Last updated:** 2025-07-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06566469

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06566469, "Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06566469. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*