# A Trial of HRS-8427 in the Treatment of Adults With Complicated Urinary Tract Infection, Including Acute Pyelonephritis

> **NCT06569056** · PHASE3 · RECRUITING · sponsor: **Jiangsu HengRui Medicine Co., Ltd.** · enrollment: 578 (estimated)

## Conditions studied

- Complicated Urinary Tract Infection(cUTI), Including Acute Pyelonephritis(AP)

## Interventions

- **DRUG:** HRS-8427
- **DRUG:** Imipenem and Cilastatin Sodium
- **DRUG:** HRS-8427 placebo
- **DRUG:** Imipenem and Cilastatin Sodium placebo

## Key facts

- **NCT ID:** NCT06569056
- **Lead sponsor:** Jiangsu HengRui Medicine Co., Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-09-25
- **Primary completion:** 2025-11
- **Final completion:** 2025-11
- **Target enrollment:** 578 (ESTIMATED)
- **Last updated:** 2025-01-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06569056

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06569056, "A Trial of HRS-8427 in the Treatment of Adults With Complicated Urinary Tract Infection, Including Acute Pyelonephritis". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT06569056. Licensed CC0.

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