Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer
Stopped Abandoned 9/23/24
Conditions
- Advanced Colon Adenocarcinoma
- Advanced Colorectal Adenocarcinoma
- Advanced Rectal Adenocarcinoma
- Metastatic Colon Adenocarcinoma
- Metastatic Colorectal Adenocarcinoma
- Metastatic Rectal Adenocarcinoma
- Stage III Colon Cancer AJCC v8
- Stage III Colorectal Cancer AJCC v8
- Stage III Rectal Cancer AJCC v8
- Stage IV Colon Cancer AJCC v8
- Stage IV Colorectal Cancer AJCC v8
- Stage IV Rectal Cancer AJCC v8
Interventions
- BIOLOGICAL: Balstilimab
- PROCEDURE: Biopsy
- PROCEDURE: Biospecimen Collection
- BIOLOGICAL: Botensilimab
- PROCEDURE: Computed Tomography
- PROCEDURE: Magnetic Resonance Imaging
- DRUG: Regorafenib
Sponsor
City of Hope Medical Center
Collaborators