# A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of Unilateral Exablate MR-guided Focused Ultrasound Subthalamotomy in Patients With Early-Stage Parkinson's Disease

> **NCT06584383** · NA · ACTIVE_NOT_RECRUITING · sponsor: **InSightec** · enrollment: 67 (actual)

## Conditions studied

- Parkinson Disease

## Interventions

- **PROCEDURE:** Exablate MRgFUS subthalamotomy
- **DRUG:** Best Medical Treatment

## Key facts

- **NCT ID:** NCT06584383
- **Lead sponsor:** InSightec
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-08-01
- **Primary completion:** 2027-09
- **Final completion:** 2029-09
- **Target enrollment:** 67 (ACTUAL)
- **Last updated:** 2026-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06584383

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06584383, "A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of Unilateral Exablate MR-guided Focused Ultrasound Subthalamotomy in Patients With Early-Stage Parkinson's Disease". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT06584383. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*