# Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.

> **NCT06603688** · PHASE4 · UNKNOWN · sponsor: **Xijing Hospital of Digestive Diseases** · enrollment: 548 (estimated)

## Conditions studied

- Helicobacter Pylori Infection
- Chronic Gastritis

## Interventions

- **DRUG:** esomeprazole
- **DRUG:** Bismuth
- **DRUG:** Amoxicillin
- **DRUG:** clarithromycin
- **DRUG:** Berberine
- **DRUG:** Minocycline

## Key facts

- **NCT ID:** NCT06603688
- **Lead sponsor:** Xijing Hospital of Digestive Diseases
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2023-11-20
- **Primary completion:** 2024-11-01
- **Final completion:** 2024-12-01
- **Target enrollment:** 548 (ESTIMATED)
- **Last updated:** 2024-09-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06603688

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06603688, "Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT06603688. Licensed CC0.

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