# Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays

> **NCT06607003** · PHASE1 · RECRUITING · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)** · enrollment: 300 (estimated)

## Conditions studied

- Malaria

## Interventions

- **BIOLOGICAL:** P. vivax challenge agent derived from PvHMB-CCE001

## Key facts

- **NCT ID:** NCT06607003
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-11-26
- **Primary completion:** 2027-11-26
- **Final completion:** 2027-11-26
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2026-04-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06607003

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06607003, "Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT06607003. Licensed CC0.

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