# Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery

> **NCT06608030** · NA · COMPLETED · sponsor: **Chinese PLA General Hospital** · enrollment: 142 (actual)

## Conditions studied

- Depression, Anxiety
- Cardiac Surgery
- S-ketamine

## Interventions

- **DRUG:** Esketamine
- **DRUG:** normal saline

## Key facts

- **NCT ID:** NCT06608030
- **Lead sponsor:** Chinese PLA General Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-09-23
- **Primary completion:** 2025-04-07
- **Final completion:** 2025-04-30
- **Target enrollment:** 142 (ACTUAL)
- **Last updated:** 2025-11-25

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06608030

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06608030, "Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT06608030. Licensed CC0.

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