# A Study to Evaluate the Effect of Food, Formulation, and a Proton Pump Inhibitor (PPI) on Calderasib (MK-1084) in Healthy Adult Participants (MK-1084-003)

> **NCT06619314** · PHASE1 · COMPLETED · sponsor: **Merck Sharp & Dohme LLC** · enrollment: 56 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** Calderasib
- **DRUG:** PPI

## Key facts

- **NCT ID:** NCT06619314
- **Lead sponsor:** Merck Sharp & Dohme LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-09-20
- **Primary completion:** 2023-11-25
- **Final completion:** 2023-11-25
- **Target enrollment:** 56 (ACTUAL)
- **Last updated:** 2026-02-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06619314

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06619314, "A Study to Evaluate the Effect of Food, Formulation, and a Proton Pump Inhibitor (PPI) on Calderasib (MK-1084) in Healthy Adult Participants (MK-1084-003)". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06619314. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*