# Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

> **NCT06627270** · PHASE2 · RECRUITING · sponsor: **Case Comprehensive Cancer Center** · enrollment: 30 (estimated)

## Conditions studied

- Oral Squamous Cell Carcinoma
- Oral Cancer
- Head and Neck Cancer
- Head and Neck Carcinoma

## Interventions

- **DRUG:** Metronidazole
- **OTHER:** Chlorhexidine

## Key facts

- **NCT ID:** NCT06627270
- **Lead sponsor:** Case Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-11
- **Primary completion:** 2026-10-01
- **Final completion:** 2027-10-01
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-03-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06627270

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06627270, "Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer". Retrieved via AI Analytics 2026-07-06 from https://api.ai-analytics.org/clinical/NCT06627270. Licensed CC0.

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