# Trained Immunity in Fungal Infection and Its Mechanism

> **NCT06628544** · EARLY_PHASE1 · COMPLETED · sponsor: **Zhongnan Hospital** · enrollment: 79 (actual)

## Conditions studied

- BCG Vaccination

## Interventions

- **BIOLOGICAL:** BCG vaccination
- **DRUG:** Metformin is administered on the day 0
- **OTHER:** Placebo
- **DRUG:** Metformin is administered on the day 9
- **DRUG:** Metformin is administered on the day 85

## Key facts

- **NCT ID:** NCT06628544
- **Lead sponsor:** Zhongnan Hospital
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-09-01
- **Primary completion:** 2023-08-31
- **Final completion:** 2023-12-01
- **Target enrollment:** 79 (ACTUAL)
- **Last updated:** 2024-10-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06628544

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06628544, "Trained Immunity in Fungal Infection and Its Mechanism". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06628544. Licensed CC0.

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