5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours

NCT06630260 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

RECRUITING

Status

182

Enrollment

OTHER

Sponsor class

Conditions

Glioblastoma Multiforme (GBM)
Glioblastoma Multiform (Grade IV Astrocytoma)
Diffuse Hemispheric Glioma, H3 G34-Mutant
Malignant Primary Gliomas

Interventions

DRUG: Avutometinib
DRUG: Defactinib
DRUG: Temozolomide

Sponsor

Institute of Cancer Research, United Kingdom

Collaborators

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