# A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012)

> **NCT06633419** · PHASE1 · COMPLETED · sponsor: **Merck Sharp & Dohme LLC** · enrollment: 14 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** Opevesostat
- **DRUG:** Prednisone
- **DRUG:** Fludrocortisone acetate
- **DRUG:** Carbamazepine

## Key facts

- **NCT ID:** NCT06633419
- **Lead sponsor:** Merck Sharp & Dohme LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-12-18
- **Primary completion:** 2025-02-12
- **Final completion:** 2025-05-13
- **Target enrollment:** 14 (ACTUAL)
- **Last updated:** 2025-05-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06633419

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06633419, "A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012)". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT06633419. Licensed CC0.

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