# Repurposing Siponimod for Alzheimer's Disease

> **NCT06639282** · PHASE2 · RECRUITING · sponsor: **St. Joseph's Hospital and Medical Center, Phoenix** · enrollment: 105 (estimated)

## Conditions studied

- Alzheimer Disease
- Mild Alzheimer Disease
- MCI With Increased Risk for Alzheimer Disease
- Cognitive Impairment, Mild

## Interventions

- **DRUG:** Siponimod
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT06639282
- **Lead sponsor:** St. Joseph's Hospital and Medical Center, Phoenix
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-08-26
- **Primary completion:** 2029-10
- **Final completion:** 2029-10
- **Target enrollment:** 105 (ESTIMATED)
- **Last updated:** 2026-03-04

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06639282

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06639282, "Repurposing Siponimod for Alzheimer's Disease". Retrieved via AI Analytics 2026-07-15 from https://api.ai-analytics.org/clinical/NCT06639282. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*