# Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder

> **NCT06642181** · PHASE1 · RECRUITING · sponsor: **Rutgers, The State University of New Jersey** · enrollment: 224 (estimated)

## Conditions studied

- Mindfulness
- Guanfacine
- Opioid Use Disorder

## Interventions

- **DRUG:** Guanfacine pharmacotherapy
- **BEHAVIORAL:** Mindfulness Oriented Recovery Enhancement (MORE)

## Key facts

- **NCT ID:** NCT06642181
- **Lead sponsor:** Rutgers, The State University of New Jersey
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-15
- **Primary completion:** 2026-08-31
- **Final completion:** 2026-09-30
- **Target enrollment:** 224 (ESTIMATED)
- **Last updated:** 2025-08-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06642181

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06642181, "Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT06642181. Licensed CC0.

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