# A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder

> **NCT06648655** · PHASE2 · TERMINATED · sponsor: **Tempero Bio, Inc.** · enrollment: 110 (actual)

## Conditions studied

- Alcohol Use Disorder (AUD)

## Interventions

- **DRUG:** TMP-301
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT06648655
- **Lead sponsor:** Tempero Bio, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2024-11-14
- **Primary completion:** 2025-10-13
- **Final completion:** 2025-11-14
- **Target enrollment:** 110 (ACTUAL)
- **Why stopped:** Study was terminated due to serious adverse event (SAE)
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06648655

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06648655, "A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT06648655. Licensed CC0.

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