# Effect of Psilocybin on the Positive Valence System in Treatment-resistant Depression

> **NCT06650800** · NA · COMPLETED · sponsor: **Centre Hospitalier Universitaire de Nīmes** · enrollment: 10 (actual)

## Conditions studied

- Depressive Disorder
- Depressive Disorder, Treatment-Resistant
- Hallucinogens
- Reinforcement, Psychology

## Interventions

- **DRUG:** Psilocybin
- **OTHER:** MRI

## Key facts

- **NCT ID:** NCT06650800
- **Lead sponsor:** Centre Hospitalier Universitaire de Nīmes
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-11-19
- **Primary completion:** 2025-03-26
- **Final completion:** 2025-06-26
- **Target enrollment:** 10 (ACTUAL)
- **Last updated:** 2025-08-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06650800

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06650800, "Effect of Psilocybin on the Positive Valence System in Treatment-resistant Depression". Retrieved via AI Analytics 2026-07-18 from https://api.ai-analytics.org/clinical/NCT06650800. Licensed CC0.

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