# Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke

> **NCT06658197** · PHASE3 · RECRUITING · sponsor: **Xuanwu Hospital, Beijing** · enrollment: 850 (estimated)

## Conditions studied

- Stroke, Ischemic
- Stroke, Acute
- Thrombosis, Brain
- Drug Effect

## Interventions

- **DRUG:** Tenecteplase
- **DRUG:** Alteplase

## Key facts

- **NCT ID:** NCT06658197
- **Lead sponsor:** Xuanwu Hospital, Beijing
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-12-25
- **Primary completion:** 2026-12-01
- **Final completion:** 2027-06-01
- **Target enrollment:** 850 (ESTIMATED)
- **Last updated:** 2026-04-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06658197

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06658197, "Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT06658197. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*