# Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot Study

> **NCT06661564** · NA · RECRUITING · sponsor: **University Hospital, Tours** · enrollment: 90 (estimated)

## Conditions studied

- Alzheimer Disease

## Interventions

- **OTHER:** Basal tear collection for the analysis of metabo-lipidomic profiles and concentrations of protein biomarkers (Tau, phosphorylated Tau, Aβ 1-40, and Aβ 1-42)
- **OTHER:** Collection of a blood sample (5 mL) for blood biomarkers analysis

## Key facts

- **NCT ID:** NCT06661564
- **Lead sponsor:** University Hospital, Tours
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-09
- **Primary completion:** 2027-07
- **Final completion:** 2027-07
- **Target enrollment:** 90 (ESTIMATED)
- **Last updated:** 2025-10-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06661564

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06661564, "Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot Study". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT06661564. Licensed CC0.

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