# Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)

> **NCT06663189** · PHASE3 · NOT_YET_RECRUITING · sponsor: **University Hospital, Strasbourg, France** · enrollment: 200 (estimated)

## Conditions studied

- Relapsing-remitting Multiple Sclerosis (RRMS)

## Interventions

- **DRUG:** treatment withdrawal
- **DRUG:** Usual DMT continuation
- **OTHER:** MRI
- **BEHAVIORAL:** Quality of Life questionnaires
- **OTHER:** Disability evaluation tests

## Key facts

- **NCT ID:** NCT06663189
- **Lead sponsor:** University Hospital, Strasbourg, France
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-01
- **Primary completion:** 2027-01
- **Final completion:** 2029-06
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2025-01-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06663189

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06663189, "Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06663189. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*