# An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older

> **NCT06666491** · PHASE3 · RECRUITING · sponsor: **GlaxoSmithKline** · enrollment: 300 (estimated)

## Conditions studied

- Malaria, Vivax

## Interventions

- **DRUG:** Tafenoquine
- **DRUG:** Primaquine
- **DRUG:** Chloroquine

## Key facts

- **NCT ID:** NCT06666491
- **Lead sponsor:** GlaxoSmithKline
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-11-13
- **Primary completion:** 2026-05-25
- **Final completion:** 2026-05-25
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2025-08-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06666491

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06666491, "An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT06666491. Licensed CC0.

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