# External Validation of the BREF Models

> **NCT06669312** · — · RECRUITING · sponsor: **Istituto Clinico Humanitas** · enrollment: 250 (estimated)

## Conditions studied

- Acute Respiratory Failure
- Oxygen Inhalation Therapy
- Respiratory Distress

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT06669312
- **Lead sponsor:** Istituto Clinico Humanitas
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-01-01
- **Primary completion:** 2027-01
- **Final completion:** 2027-01
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2025-07-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06669312

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06669312, "External Validation of the BREF Models". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06669312. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*