# Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment

> **NCT06669546** · NA · RECRUITING · sponsor: **University of Bern** · enrollment: 60 (estimated)

## Conditions studied

- Cognitive Decline
- Alzheimer Disease
- Subjective Cognitive Decline (SCD)
- Mild Cognitive Impairment (MCI)
- Cognitive Impairment, Mild

## Interventions

- **OTHER:** Phase-locked auditory stimulation (PLAS)
- **OTHER:** Sham Phase-Locked Auditory Stimulation

## Key facts

- **NCT ID:** NCT06669546
- **Lead sponsor:** University of Bern
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-02-21
- **Primary completion:** 2028-05
- **Final completion:** 2028-12
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2026-04-03

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06669546

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06669546, "Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT06669546. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*