# Tetra-modality Bladder Preservation Strategies in Muscle-invasive Bladder Cancer: TURBT+ Chemo/Immunotherapy+ Radiation Therapy+ Maintenance Immunotherapy vs. W&W

> **NCT06686381** · PHASE2 · NOT_YET_RECRUITING · sponsor: **American University of Beirut Medical Center** · enrollment: 80 (estimated)

## Conditions studied

- Muscle-invasive Bladder Cancer

## Interventions

- **PROCEDURE:** Maximum TURBT
- **DRUG:** Chemotherapy + Immunotherapy Induction
- **RADIATION:** Radiotherapy
- **DRUG:** Immunotherapy Maintenance
- **OTHER:** Watchful waiting with supportive care

## Key facts

- **NCT ID:** NCT06686381
- **Lead sponsor:** American University of Beirut Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-04-15
- **Primary completion:** 2028-08
- **Final completion:** 2028-08-15
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2025-02-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06686381

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06686381, "Tetra-modality Bladder Preservation Strategies in Muscle-invasive Bladder Cancer: TURBT+ Chemo/Immunotherapy+ Radiation Therapy+ Maintenance Immunotherapy vs. W&W". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT06686381. Licensed CC0.

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