# Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With Periodontal Health and Stage III Periodontitis, Considering Both Smokers and Non-Smokers, Before and After Non-Surgical Periodontal Therapy

> **NCT06687005** · — · ACTIVE_NOT_RECRUITING · sponsor: **Tugba Aydin** · enrollment: 45 (actual)

## Conditions studied

- Periodontitis (Stage 3)
- Gremlin-1
- Syndecan 4
- Interleukin 1-beta

## Interventions

- **PROCEDURE:** non-surgical periodontal therapy

## Key facts

- **NCT ID:** NCT06687005
- **Lead sponsor:** Tugba Aydin
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-04-01
- **Primary completion:** 2024-12-15
- **Final completion:** 2024-12-15
- **Target enrollment:** 45 (ACTUAL)
- **Last updated:** 2024-11-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06687005

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06687005, "Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With Periodontal Health and Stage III Periodontitis, Considering Both Smokers and Non-Smokers, Before and After Non-Surgical Periodontal Therapy". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT06687005. Licensed CC0.

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