# Clinical Study to Evaluate the Safety and the Efficacy of EscharEx Drug Product (EX-03 Formulation) and Its Placebo Compared to Collagenase, Non-surgical Standard of Care, in Patients With Venous Leg Ulcers

> **NCT06690177** · PHASE2 · NOT_YET_RECRUITING · sponsor: **MediWound Ltd** · enrollment: 45 (estimated)

## Conditions studied

- Venus Leg Ulcers

## Interventions

- **DRUG:** EscharEx (EX-03)
- **DRUG:** Placebo (Gel vehicle)

## Key facts

- **NCT ID:** NCT06690177
- **Lead sponsor:** MediWound Ltd
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-04-30
- **Primary completion:** 2027-12-30
- **Final completion:** 2028-09-30
- **Target enrollment:** 45 (ESTIMATED)
- **Last updated:** 2024-11-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06690177

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06690177, "Clinical Study to Evaluate the Safety and the Efficacy of EscharEx Drug Product (EX-03 Formulation) and Its Placebo Compared to Collagenase, Non-surgical Standard of Care, in Patients With Venous Leg Ulcers". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06690177. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*