# AYLo - AutoimmunitY and Loss of y

> **NCT06696027** · — · RECRUITING · sponsor: **University of Bonn** · enrollment: 500 (estimated)

## Conditions studied

- Giant Cell Arteritis (GCA)
- Polymyalgia Rheumatica (PMR)
- ANCA Associated Vasculitis (AAV)
- Idiopathic Inflammatory Myopathies
- IgG4-Related Diseases
- Rheumatoid Arthritis (RA)
- Psoriatic Arthritis (PsA)
- Connective Tissue Disease
- Sarcoidosis
- Interstitial Lung Disease Due to Systemic Disease (Disorder)
- Interstitial Lung Disease (ILD)
- Asthma Bronchiale
- COPD

## Interventions

- **DIAGNOSTIC_TEST:** Single nucleotide polymorphisms (SNP)
- **DIAGNOSTIC_TEST:** 3'mRNA sequencing
- **DIAGNOSTIC_TEST:** Enzyme-linked immunosorbent assay (ELISA) and Legendplex Array
- **DIAGNOSTIC_TEST:** Flow Cytometry
- **DIAGNOSTIC_TEST:** Laboratory assessment
- **DIAGNOSTIC_TEST:** Assessment of Pulmonary Involvement

## Key facts

- **NCT ID:** NCT06696027
- **Lead sponsor:** University of Bonn
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-11-15
- **Primary completion:** 2025-12
- **Final completion:** 2026-07
- **Target enrollment:** 500 (ESTIMATED)
- **Last updated:** 2025-04-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06696027

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06696027, "AYLo - AutoimmunitY and Loss of y". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06696027. Licensed CC0.

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