# A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

> **NCT06704724** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Pfizer** · enrollment: 30 (actual)

## Conditions studied

- Carcinoma, Pancreatic Ductal
- Colorectal Neoplasms
- Carcinoma, Non-Small-Cell Lung

## Interventions

- **DRUG:** PF-07985045
- **COMBINATION_PRODUCT:** Gemcitabine
- **COMBINATION_PRODUCT:** Nab-paclitaxel
- **COMBINATION_PRODUCT:** Cetuximab
- **COMBINATION_PRODUCT:** Fluorouracil
- **COMBINATION_PRODUCT:** Oxaliplatin
- **COMBINATION_PRODUCT:** Leucovorin
- **COMBINATION_PRODUCT:** Bevacizumab
- **COMBINATION_PRODUCT:** Pembrolizumab
- **COMBINATION_PRODUCT:** Sasanlimab
- **COMBINATION_PRODUCT:** pemetrexed
- **COMBINATION_PRODUCT:** Cisplatin
- **COMBINATION_PRODUCT:** Paclitaxel
- **COMBINATION_PRODUCT:** Carboplatin
- **COMBINATION_PRODUCT:** PF-07284892

## Key facts

- **NCT ID:** NCT06704724
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-12-10
- **Primary completion:** 2028-03-11
- **Final completion:** 2029-03-11
- **Target enrollment:** 30 (ACTUAL)
- **Last updated:** 2026-03-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06704724

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06704724, "A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.". Retrieved via AI Analytics 2026-07-24 from https://api.ai-analytics.org/clinical/NCT06704724. Licensed CC0.

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