# Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial)

> **NCT06706258** · PHASE2 · RECRUITING · sponsor: **The University of Texas Health Science Center, Houston** · enrollment: 400 (estimated)

## Conditions studied

- Acute Kidney Injury

## Interventions

- **DRUG:** Protonix (Pantoprazole) 40 mg q 12 hrs for 3 days
- **DRUG:** Pepcid (Famotidine) 20 mg q 12 hrs for 3 days

## Key facts

- **NCT ID:** NCT06706258
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-01-24
- **Primary completion:** 2026-12-01
- **Final completion:** 2027-07-01
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2025-05-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06706258

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06706258, "Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial)". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT06706258. Licensed CC0.

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