# Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

> **NCT06721520** · PHASE2,PHASE3 · RECRUITING · sponsor: **The Cleveland Clinic** · enrollment: 170 (estimated)

## Conditions studied

- Esophageal Cancer Surgery
- Esophagectomy
- Delayed Gastric Emptying Following Procedure
- Esophageal Diseases
- Esophageal Achalasia
- Pylorus Dysfunction
- Esophageal Dysmotility

## Interventions

- **BIOLOGICAL:** Botulinum Toxin A (Botox )
- **PROCEDURE:** Pyloromyotomy

## Key facts

- **NCT ID:** NCT06721520
- **Lead sponsor:** The Cleveland Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-12-03
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-05-31
- **Target enrollment:** 170 (ESTIMATED)
- **Last updated:** 2026-02-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06721520

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06721520, "Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy". Retrieved via AI Analytics 2026-07-06 from https://api.ai-analytics.org/clinical/NCT06721520. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*