# GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification

> **NCT06722521** · PHASE4 · RECRUITING · sponsor: **Asan Medical Center** · enrollment: 7435 (estimated)

## Conditions studied

- Primary Prevention
- Vascular Calcification

## Interventions

- **DRUG:** Pitavastatin 4mg and ezetimibe 10mg, taken once daily
- **DRUG:** Pitavastatin 2 mg with aspirin 100 mg, taken once daily.

## Key facts

- **NCT ID:** NCT06722521
- **Lead sponsor:** Asan Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-07-09
- **Primary completion:** 2032-06-30
- **Final completion:** 2032-10-31
- **Target enrollment:** 7435 (ESTIMATED)
- **Last updated:** 2025-08-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06722521

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06722521, "GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification". Retrieved via AI Analytics 2026-08-11 from https://api.ai-analytics.org/clinical/NCT06722521. Licensed CC0.

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