Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer
Conditions
- Head and Neck Cancers- Squamous Cell
- Head and Neck Cancer
- Solid Tumors
- HNSCC
- SCC - Squamous Cell Carcinoma
- SCCHN
- Head Neck Cancer
- Head and Neck Squamous Cell Cancer
- Squamous Cell Carcinoma of the Head and Neck
- Squamous Cell Carcinoma, Head And Neck
- Squamous Cell Head and Neck Carcinoma
- Oral Cavity
- Oral Cavity Carcinoma
Interventions
- BIOLOGICAL: VRP-encapsulated saRNA encoding IL-12 (1 x 10^9 viral particles per injection)
- DRUG: Pembrolizumab (KEYTRUDA®)
- BIOLOGICAL: VRP-encapsulated saRNA encoding IL-12 (3 x 10^8 viral particles per injection)
Sponsor
VLP Therapeutics
Collaborators