# Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.

> **NCT06741566** · EARLY_PHASE1 · RECRUITING · sponsor: **Minia University** · enrollment: 150 (estimated)

## Conditions studied

- Post Operative Cognitive Dysfunction

## Interventions

- **DRUG:** intranasal saline group
- **DRUG:** intranasal insulin
- **DRUG:** Intranasal dexmedetomidine

## Key facts

- **NCT ID:** NCT06741566
- **Lead sponsor:** Minia University
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-12-27
- **Primary completion:** 2026-05-14
- **Final completion:** 2026-05-15
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2026-05-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06741566

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06741566, "Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06741566. Licensed CC0.

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