# A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer

> **NCT06747338** · PHASE3 · RECRUITING · sponsor: **Shanghai JMT-Bio Inc.** · enrollment: 520 (estimated)

## Conditions studied

- Early or Locally Advanced HER2-positive Breast Cancer

## Interventions

- **DRUG:** KN026
- **DRUG:** HB1801
- **DRUG:** Pertuzumab
- **DRUG:** Trastuzumab
- **DRUG:** Docetaxel
- **DRUG:** Carboplatin

## Key facts

- **NCT ID:** NCT06747338
- **Lead sponsor:** Shanghai JMT-Bio Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-12-16
- **Primary completion:** 2026-12-16
- **Final completion:** 2027-12-16
- **Target enrollment:** 520 (ESTIMATED)
- **Last updated:** 2025-04-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06747338

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06747338, "A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06747338. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*