# Effect of Different Apical Actions on Local Inflammatory Mediators and Pain

> **NCT06760312** · NA · COMPLETED · sponsor: **Izmir Katip Celebi University** · enrollment: 75 (actual)

## Conditions studied

- Postoperative Dental Pain
- Pulp Disease, Dental
- Pulpitis - Irreversible

## Interventions

- **PROCEDURE:** Root canal shaping with Continuous Rotation
- **PROCEDURE:** Root canal shaping with Apical Reverse
- **PROCEDURE:** Root canal shaping is conducted with Apical slow-down kinematic.

## Key facts

- **NCT ID:** NCT06760312
- **Lead sponsor:** Izmir Katip Celebi University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-02-01
- **Primary completion:** 2025-05-01
- **Final completion:** 2025-07-01
- **Target enrollment:** 75 (ACTUAL)
- **Last updated:** 2025-07-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06760312

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06760312, "Effect of Different Apical Actions on Local Inflammatory Mediators and Pain". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT06760312. Licensed CC0.

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