# Clinical Study of Low-dose Interval Radiotherapy Combined With Tirelizumab and SOX Chemotherapy Neoadjuvant Therapy for Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

> **NCT06766578** · PHASE2 · RECRUITING · sponsor: **Shandong Provincial Hospital** · enrollment: 32 (estimated)

## Conditions studied

- Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

## Interventions

- **RADIATION:** Neoadjuvant Therapy(5×3Gy radiotherapy)
- **DRUG:** Neoadjuvant Therapy(tirelizumab, oxaliplatin, S-1)
- **PROCEDURE:** Surgical treatment
- **DRUG:** Adjuvant therapy(SOX chemotherapy)

## Key facts

- **NCT ID:** NCT06766578
- **Lead sponsor:** Shandong Provincial Hospital
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-12-30
- **Primary completion:** 2027-12-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 32 (ESTIMATED)
- **Last updated:** 2026-04-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06766578

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06766578, "Clinical Study of Low-dose Interval Radiotherapy Combined With Tirelizumab and SOX Chemotherapy Neoadjuvant Therapy for Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma". Retrieved via AI Analytics 2026-07-25 from https://api.ai-analytics.org/clinical/NCT06766578. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*