# Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome

> **NCT06779890** · PHASE4 · RECRUITING · sponsor: **Georgia Tsaousi** · enrollment: 84 (estimated)

## Conditions studied

- Brain Edema Caused by Drugs
- Cerebral Oxygenation

## Interventions

- **DRUG:** Sevoflurane
- **DRUG:** Desflurane

## Key facts

- **NCT ID:** NCT06779890
- **Lead sponsor:** Georgia Tsaousi
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-05-12
- **Primary completion:** 2026-09-30
- **Final completion:** 2026-09-30
- **Target enrollment:** 84 (ESTIMATED)
- **Last updated:** 2025-10-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06779890

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06779890, "Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06779890. Licensed CC0.

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