FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

NCT06780787 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

26

Enrollment

OTHER

Sponsor class

Conditions

Rectal Adenocarcinoma
Stage IIA Rectal Cancer AJCC v8
Stage III Rectal Cancer AJCC v8

Interventions

BIOLOGICAL: Balstilimab
PROCEDURE: Biospecimen Collection
BIOLOGICAL: Botensilimab
DRUG: Capecitabine
PROCEDURE: Computed Tomography
PROCEDURE: Digital Rectal Examination
PROCEDURE: Endoscopic Biopsy
DRUG: Fluorouracil
DRUG: Leucovorin Calcium
PROCEDURE: Magnetic Resonance Imaging
DRUG: Oxaliplatin
RADIATION: Radiation Therapy
PROCEDURE: Sigmoidoscopy

Sponsor

City of Hope Medical Center

Collaborators

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