# Efficacy of taVNS Versus Sham Stimulation in Reduing Depressive Symptoms in Patients With Epilepsy: a Multi-center, Double-blinded, Randomized, 20-week, Parallel-arm, Superiority Study

> **NCT06794034** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 158 (estimated)

## Conditions studied

- Depressive Symptoms in Patients With Epilepsy

## Interventions

- **DEVICE:** Intervention
- **DEVICE:** Sham Comparator

## Key facts

- **NCT ID:** NCT06794034
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-04-01
- **Primary completion:** 2025-12-30
- **Final completion:** 2025-12-31
- **Target enrollment:** 158 (ESTIMATED)
- **Last updated:** 2025-01-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06794034

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06794034, "Efficacy of taVNS Versus Sham Stimulation in Reduing Depressive Symptoms in Patients With Epilepsy: a Multi-center, Double-blinded, Randomized, 20-week, Parallel-arm, Superiority Study". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT06794034. Licensed CC0.

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