Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)

NCT06802315 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

38

Enrollment

OTHER

Sponsor class

Conditions

Acute Myeloid Leukemia, Relapsed, Adult
Acute Myeloid Leukemia Refractory
Chronic Myeloid Leukemia - Accelerated Phase
Myelodysplastic Syndromes

Interventions

RADIATION: Intensity modulated total marrow irradiation
DRUG: Cyclophosphamide (CTX)
DRUG: Fludarabine (Fludara)
DRUG: Busulfan (conditioning for ALLO Transplant)

Sponsor

University of Illinois at Chicago