# Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)

> **NCT06803745** · NA · RECRUITING · sponsor: **Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins** · enrollment: 160 (estimated)

## Conditions studied

- Acute Leukemia
- Acute Lymphoblastic Lymphoma

## Interventions

- **RADIATION:** 200 cGy or 400 cGy total body irradiation (TBI)

## Key facts

- **NCT ID:** NCT06803745
- **Lead sponsor:** Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-27
- **Primary completion:** 2030-03-31
- **Final completion:** 2030-09-30
- **Target enrollment:** 160 (ESTIMATED)
- **Last updated:** 2026-04-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06803745

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06803745, "Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT06803745. Licensed CC0.

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